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Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report
This report presents anatomo‐histopathological, immunohistochemical and molecular analyses of an asymptomatic female dog naturally infected with Leishmania (Leishmania) infantum and her four pups. In addition to routine serological tests, the mother's positivity was confirmed by real‐time PCR o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650230/ https://www.ncbi.nlm.nih.gov/pubmed/37669416 http://dx.doi.org/10.1002/vms3.1254 |
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author | Heil, Ana Carina de Melo Lima Waterloo, Mateus Guerra, Juliana Mariotti Ferreira, Ana Maria Reis da Silva Leite, Juliana |
author_facet | Heil, Ana Carina de Melo Lima Waterloo, Mateus Guerra, Juliana Mariotti Ferreira, Ana Maria Reis da Silva Leite, Juliana |
author_sort | Heil, Ana Carina |
collection | PubMed |
description | This report presents anatomo‐histopathological, immunohistochemical and molecular analyses of an asymptomatic female dog naturally infected with Leishmania (Leishmania) infantum and her four pups. In addition to routine serological tests, the mother's positivity was confirmed by real‐time PCR of a bone marrow sample; the placenta and ovaries, however, were negative with the same analysis. The pups presented no positivity in any of the techniques used. It is suggested that the gestational period and factors related to the female's immunological condition cause greater variability in the occurrence of vertical infection. |
format | Online Article Text |
id | pubmed-10650230 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106502302023-09-05 Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report Heil, Ana Carina de Melo Lima Waterloo, Mateus Guerra, Juliana Mariotti Ferreira, Ana Maria Reis da Silva Leite, Juliana Vet Med Sci DOGS This report presents anatomo‐histopathological, immunohistochemical and molecular analyses of an asymptomatic female dog naturally infected with Leishmania (Leishmania) infantum and her four pups. In addition to routine serological tests, the mother's positivity was confirmed by real‐time PCR of a bone marrow sample; the placenta and ovaries, however, were negative with the same analysis. The pups presented no positivity in any of the techniques used. It is suggested that the gestational period and factors related to the female's immunological condition cause greater variability in the occurrence of vertical infection. John Wiley and Sons Inc. 2023-09-05 /pmc/articles/PMC10650230/ /pubmed/37669416 http://dx.doi.org/10.1002/vms3.1254 Text en © 2023 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | DOGS Heil, Ana Carina de Melo Lima Waterloo, Mateus Guerra, Juliana Mariotti Ferreira, Ana Maria Reis da Silva Leite, Juliana Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report |
title | Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report |
title_full | Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report |
title_fullStr | Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report |
title_full_unstemmed | Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report |
title_short | Histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by Leishmania (Leishmania) infantum – Case report |
title_sort | histopathological, immunohistochemical and molecular analyses of foetuses from a female dog naturally infected by leishmania (leishmania) infantum – case report |
topic | DOGS |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650230/ https://www.ncbi.nlm.nih.gov/pubmed/37669416 http://dx.doi.org/10.1002/vms3.1254 |
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