The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases

DNA methylation is an epigenetic mechanism that regulates gene expression without altering gene sequences in health and disease. DNA methyltransferases (DNMTs) are enzymes responsible for DNA methylation, and their dysregulation is both a pathogenic mechanism of disease and a therapeutic target. DNM...

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Detalles Bibliográficos
Autores principales: Emon, Isaac M., Al-Qazazi, Ruaa, Rauh, Michael J., Archer, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650407/
https://www.ncbi.nlm.nih.gov/pubmed/37947606
http://dx.doi.org/10.3390/cells12212528

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