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Treating Parkinson’s Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration

Parkinson’s disease (PD) is the most common movement disorder, characterized by the progressive loss of dopaminergic neurons from the nigrostriatal system. Currently, there is no treatment that retards disease progression or reverses damage prior to the time of clinical diagnosis. Mesenchymal stem c...

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Detalles Bibliográficos
Autores principales: Mendes-Pinheiro, Bárbara, Campos, Jonas, Marote, Ana, Soares-Cunha, Carina, Nickels, Sarah L., Monzel, Anna S., Cibrão, Jorge R., Loureiro-Campos, Eduardo, Serra, Sofia C., Barata-Antunes, Sandra, Duarte-Silva, Sara, Pinto, Luísa, Schwamborn, Jens C., Salgado, António J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650433/
https://www.ncbi.nlm.nih.gov/pubmed/37947643
http://dx.doi.org/10.3390/cells12212565