Cargando…
Treating Parkinson’s Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration
Parkinson’s disease (PD) is the most common movement disorder, characterized by the progressive loss of dopaminergic neurons from the nigrostriatal system. Currently, there is no treatment that retards disease progression or reverses damage prior to the time of clinical diagnosis. Mesenchymal stem c...
Autores principales: | Mendes-Pinheiro, Bárbara, Campos, Jonas, Marote, Ana, Soares-Cunha, Carina, Nickels, Sarah L., Monzel, Anna S., Cibrão, Jorge R., Loureiro-Campos, Eduardo, Serra, Sofia C., Barata-Antunes, Sandra, Duarte-Silva, Sara, Pinto, Luísa, Schwamborn, Jens C., Salgado, António J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650433/ https://www.ncbi.nlm.nih.gov/pubmed/37947643 http://dx.doi.org/10.3390/cells12212565 |
Ejemplares similares
-
Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response
por: Mendes-Pinheiro, Bárbara, et al.
Publicado: (2021) -
A robust protocol for the generation of human midbrain organoids
por: Zagare, Alise, et al.
Publicado: (2021) -
Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model
por: Mendes-Pinheiro, Bárbara, et al.
Publicado: (2019) -
Cerebral Malaria Model Applying Human Brain Organoids
por: Silva-Pedrosa, Rita, et al.
Publicado: (2023) -
Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders
por: Pinho, Andreia G., et al.
Publicado: (2020)