Cargando…
Rethinking IL-1 Antagonism in Respiratory Viral Infections: A Role for IL-1 Signaling in the Development of Antiviral T Cell Immunity
IL-1R integrates signals from IL-1α and IL-1β, and it is widely expressed across tissues and immune cell types. While the expression pattern and function of IL-1R within the innate immune system is well studied, its role in adaptive immunity, particularly within the CD8 T cell compartment, remains u...
Autores principales: | Van Den Eeckhout, Bram, Ballegeer, Marlies, De Clercq, Jozefien, Burg, Elianne, Saelens, Xavier, Vandekerckhove, Linos, Gerlo, Sarah |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650641/ https://www.ncbi.nlm.nih.gov/pubmed/37958758 http://dx.doi.org/10.3390/ijms242115770 |
Ejemplares similares
-
Specific targeting of IL-1β activity to CD8(+) T cells allows for safe use as a vaccine adjuvant
por: Van Den Eeckhout, Bram, et al.
Publicado: (2020) -
Selective IL-1 activity on CD8(+) T cells empowers antitumor immunity and synergizes with neovasculature-targeted TNF for full tumor eradication
por: Van Den Eeckhout, Bram, et al.
Publicado: (2021) -
Cell-Mediated Responses to Human Metapneumovirus Infection
por: Ballegeer, Marlies, et al.
Publicado: (2020) -
Interleukin-1 as Innate Mediator of T Cell Immunity
por: Van Den Eeckhout, Bram, et al.
Publicado: (2021) -
An Inside Job: Applications of Intracellular Single Domain Antibodies
por: Soetens, Eline, et al.
Publicado: (2020)