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MLH1 Methylation Testing as an Integral Component of Universal Endometrial Cancer Screening—A Critical Appraisal

SIMPLE SUMMARY: Often in endometrial cancer (EC), the mismatch repair (MMR) system, which helps fix DNA mistakes, goes haywire because of MLH1 promoter hypermethylation (MLH1-PHM). We set out to find out how many ECs have MLH1-PHM, understand the impact of reflex MLH1-PHM testing and evaluate the as...

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Detalles Bibliográficos
Autores principales:	Plotkin, Anna, Olkhov-Mitsel, Ekaterina, Nofech-Mozes, Sharon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650699/ https://www.ncbi.nlm.nih.gov/pubmed/37958361 http://dx.doi.org/10.3390/cancers15215188

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