High-risk subtypes of chronic lymphocytic leukemia are detectable as early as 16 years prior to diagnosis

Chronic lymphocytic leukemia (CLL) is preceded by monoclonal B-cell lymphocytosis (MBL), a CLL precursor state with a prevalence of up to 12% in aged individuals; however, the duration of MBL and the mechanisms of its evolution to CLL remain largely unknown. In this study, we sequenced the B-cell re...

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Detalles Bibliográficos
Autores principales: Kolijn, P. Martijn, Hosnijeh, Fatemeh Saberi, Späth, Florentin, Hengeveld, Paul J., Agathangelidis, Andreas, Saleh, Manal, Casabonne, Delphine, Benavente, Yolanda, Jerkeman, Mats, Agudo, Antonio, Barricarte, Aurelio, Besson, Caroline, Sánchez, Maria-Jose, Chirlaque, María-Dolores, Masala, Giovanna, Sacerdote, Carlotta, Grioni, Sara, Schulze, Matthias B., Nieters, Alexandra, Engelfriet, Peter, Hultdin, Magnus, McKay, James D., Vermeulen, Roel C.H., Langerak, Anton W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10650964/
https://www.ncbi.nlm.nih.gov/pubmed/34662377
http://dx.doi.org/10.1182/blood.2021012890

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