Cargando…
Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study
INTRODUCTION: Most clinicians give sedatives and analgesics according to their professional experience and the patient's estimated need for sedation. However, this approach is prone to error. Inadequate monitoring of sedation and analgesia may contribute to adverse outcomes and complications. W...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065097/ https://www.ncbi.nlm.nih.gov/pubmed/15693968 http://dx.doi.org/10.1186/cc2977 |
_version_ | 1782123349092073472 |
---|---|
author | Triltsch, Andreas E Nestmann, Grit Orawa, Helmut Moshirzadeh, Maryam Sander, Michael Große, Joachim Genähr, Arka Konertz, Wolfgang Spies, Claudia D |
author_facet | Triltsch, Andreas E Nestmann, Grit Orawa, Helmut Moshirzadeh, Maryam Sander, Michael Große, Joachim Genähr, Arka Konertz, Wolfgang Spies, Claudia D |
author_sort | Triltsch, Andreas E |
collection | PubMed |
description | INTRODUCTION: Most clinicians give sedatives and analgesics according to their professional experience and the patient's estimated need for sedation. However, this approach is prone to error. Inadequate monitoring of sedation and analgesia may contribute to adverse outcomes and complications. With this in mind, data obtained continuously using nonstimulating methods such as bispectral index (BIS) may have benefits in comparison with clinical monitoring of sedation. The aim of this prospective observational trial was to evaluate the use of electroencephalographic (EEG) BIS for monitoring sedation in paediatric intensive care unit (PICU) patients. METHODS: Forty paediatric patients (<18 years) were sedated for mechanical ventilation in a cardiac surgical and general PICU. In each paediatric patient BIS and COMFORT score were obtained. The study protocol did not influence ongoing PICU therapy. BIS and corresponding COMFORT score were collected three times for each patient. Measurements with the best starting EEG impedances were analyzed further. Deep sedation was defined as a COMFORT score between 8 and 16, and light sedation as a score between 17 and 26. Biometric and physiological data, and Pediatric Risk of Mortality III scores were also recorded. RESULTS: There was a good correlation (Spearman's rho 0.651; P = 0.001) between BIS and COMFORT score in the presence of deep sedation and low starting impedance. Receiver operating characteristic (ROC) analysis revealed best discrimination between deep and light sedation at a BIS level of 83. CONCLUSION: In the presence of deep sedation, BIS correlated satisfactorily with COMFORT score results if low EEG impedances were guaranteed. |
format | Text |
id | pubmed-1065097 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-10650972005-03-16 Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study Triltsch, Andreas E Nestmann, Grit Orawa, Helmut Moshirzadeh, Maryam Sander, Michael Große, Joachim Genähr, Arka Konertz, Wolfgang Spies, Claudia D Crit Care Research INTRODUCTION: Most clinicians give sedatives and analgesics according to their professional experience and the patient's estimated need for sedation. However, this approach is prone to error. Inadequate monitoring of sedation and analgesia may contribute to adverse outcomes and complications. With this in mind, data obtained continuously using nonstimulating methods such as bispectral index (BIS) may have benefits in comparison with clinical monitoring of sedation. The aim of this prospective observational trial was to evaluate the use of electroencephalographic (EEG) BIS for monitoring sedation in paediatric intensive care unit (PICU) patients. METHODS: Forty paediatric patients (<18 years) were sedated for mechanical ventilation in a cardiac surgical and general PICU. In each paediatric patient BIS and COMFORT score were obtained. The study protocol did not influence ongoing PICU therapy. BIS and corresponding COMFORT score were collected three times for each patient. Measurements with the best starting EEG impedances were analyzed further. Deep sedation was defined as a COMFORT score between 8 and 16, and light sedation as a score between 17 and 26. Biometric and physiological data, and Pediatric Risk of Mortality III scores were also recorded. RESULTS: There was a good correlation (Spearman's rho 0.651; P = 0.001) between BIS and COMFORT score in the presence of deep sedation and low starting impedance. Receiver operating characteristic (ROC) analysis revealed best discrimination between deep and light sedation at a BIS level of 83. CONCLUSION: In the presence of deep sedation, BIS correlated satisfactorily with COMFORT score results if low EEG impedances were guaranteed. BioMed Central 2005 2004-11-10 /pmc/articles/PMC1065097/ /pubmed/15693968 http://dx.doi.org/10.1186/cc2977 Text en Copyright © 2004 Triltsch et al., licensee BioMed Central Ltd. |
spellingShingle | Research Triltsch, Andreas E Nestmann, Grit Orawa, Helmut Moshirzadeh, Maryam Sander, Michael Große, Joachim Genähr, Arka Konertz, Wolfgang Spies, Claudia D Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
title | Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
title_full | Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
title_fullStr | Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
title_full_unstemmed | Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
title_short | Bispectral index versus COMFORT score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
title_sort | bispectral index versus comfort score to determine the level of sedation in paediatric intensive care unit patients: a prospective study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065097/ https://www.ncbi.nlm.nih.gov/pubmed/15693968 http://dx.doi.org/10.1186/cc2977 |
work_keys_str_mv | AT triltschandrease bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT nestmanngrit bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT orawahelmut bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT moshirzadehmaryam bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT sandermichael bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT großejoachim bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT genahrarka bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT konertzwolfgang bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy AT spiesclaudiad bispectralindexversuscomfortscoretodeterminethelevelofsedationinpaediatricintensivecareunitpatientsaprospectivestudy |