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Computational insights on the hydride and proton transfer mechanisms of L-proline dehydrogenase
L-Proline dehydrogenase (ProDH) is a flavin-dependent oxidoreductase, which catalyzes the oxidation of L-proline to (S)-1-pyrroline-5-carboxylate. Based on the experimental studies, a stepwise proton and hydride transfer mechanism is supported. According to this mechanism, the amino group of L-proli...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651016/ https://www.ncbi.nlm.nih.gov/pubmed/37967056 http://dx.doi.org/10.1371/journal.pone.0290901 |