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Low levels of mouse sperm chromatin fragmentation delay embryo development

We previously demonstrated that MnCl(2) induces double-stranded DNA breaks in sperm in a process that we term as sperm chromatin fragmentation. Here, we tested if the levels of double-stranded DNA breaks were corelated to the concentration of MnCl(2), and we compared this to another agent that cause...

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Detalles Bibliográficos
Autores principales: Nguyen, Hieu, Ribas-Maynou, Jordi, Wu, Hongwen, Quon, Beverly, Inouye, Tracy, Walker, Brienne, Langaman, Caitlin, Huang, Thomas T F, Ward, W Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651064/
https://www.ncbi.nlm.nih.gov/pubmed/37658763
http://dx.doi.org/10.1093/biolre/ioad106