Cargando…
Low levels of mouse sperm chromatin fragmentation delay embryo development
We previously demonstrated that MnCl(2) induces double-stranded DNA breaks in sperm in a process that we term as sperm chromatin fragmentation. Here, we tested if the levels of double-stranded DNA breaks were corelated to the concentration of MnCl(2), and we compared this to another agent that cause...
Autores principales: | Nguyen, Hieu, Ribas-Maynou, Jordi, Wu, Hongwen, Quon, Beverly, Inouye, Tracy, Walker, Brienne, Langaman, Caitlin, Huang, Thomas T F, Ward, W Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651064/ https://www.ncbi.nlm.nih.gov/pubmed/37658763 http://dx.doi.org/10.1093/biolre/ioad106 |
Ejemplares similares
-
Sperm degradation after vasectomy follows a sperm chromatin fragmentation-dependent mechanism causing DNA breaks in the toroid linker regions
por: Ribas-Maynou, Jordi, et al.
Publicado: (2022) -
An intracellular, non-oxidative factor activates in vitro chromatin fragmentation in pig sperm
por: Viñolas-Vergés, Estel, et al.
Publicado: (2023) -
Chromatin condensation but not DNA integrity of pig sperm is greater in the sperm-rich fraction
por: Viñolas-Vergés, Estel, et al.
Publicado: (2023) -
Complete Chromatin Decondensation of Pig Sperm Is Required to Analyze Sperm DNA Breaks With the Comet Assay
por: Ribas-Maynou, Jordi, et al.
Publicado: (2021) -
Direct but Not Indirect Methods Correlate the Percentages of Sperm With Altered Chromatin to the Intensity of Chromatin Damage
por: Ribas-Maynou, Jordi, et al.
Publicado: (2021)