Cargando…
Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility
A few recent, large, well-publicized trials in critical care medicine have been stopped for futility. In the critical care setting, stopping for futility means that independent review committees have elected to stop the trial early – based on predetermined rules – since the likelihood of finding a t...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1065108/ https://www.ncbi.nlm.nih.gov/pubmed/15693981 http://dx.doi.org/10.1186/cc3013 |