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Induced regeneration of articular cartilage – identification of a dormant regeneration program for a non-regenerative tissue

A mouse organoid culture model was developed to regenerate articular cartilage by sequential treatment with BMP2 and BMP9 (or GDF2) that parallels induced joint regeneration at digit amputation wounds in vivo. BMP9-induced chondrogenesis was used to identify clonal cell lines for articular chondrocy...

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Detalles Bibliográficos
Autores principales:	Lin, Yu-Lieh, Yu, Ling, Yan, Mingquan, Zimmel, Katherine, Qureshi, Osama, Imholt, Felisha, Li, Tao, Ivanov, Ivan, Brunauer, Regina, Dawson, Lindsay, Muneoka, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651102/ https://www.ncbi.nlm.nih.gov/pubmed/37882667 http://dx.doi.org/10.1242/dev.201894

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