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KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila

Histone-modifying proteins play important roles in the precise regulation of the transcriptional programs that coordinate development. KDM5 family proteins interact with chromatin through demethylation of H3K4me3 as well as demethylase-independent mechanisms that remain less understood. To gain fund...

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Detalles Bibliográficos
Autores principales: Rogers, Michael F., Marshall, Owen J., Secombe, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651110/
https://www.ncbi.nlm.nih.gov/pubmed/37800333
http://dx.doi.org/10.1242/dev.202024