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Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs

Many bacteria use CRISPR–Cas systems to combat mobile genetic elements, such as bacteriophages and plasmids(1). In turn, these invasive elements have evolved anti-CRISPR proteins to block host immunity(2,3). Here we unveil a distinct type of CRISPR–Cas Inhibition strategy that is based on small non-...

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Detalles Bibliográficos
Autores principales: Camara-Wilpert, Sarah, Mayo-Muñoz, David, Russel, Jakob, Fagerlund, Robert D., Madsen, Jonas S., Fineran, Peter C., Sørensen, Søren J., Pinilla-Redondo, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651486/
https://www.ncbi.nlm.nih.gov/pubmed/37853129
http://dx.doi.org/10.1038/s41586-023-06612-5