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Deriving protein binding‐corrected chemical concentrations for in vitro testing

Extracellular chemical concentrations are considered physiologically relevant for in vitro testing and are evaluated in traditional in vitro systems using cell culture media containing 5%–10% fetal bovine serum (FBS). However, depending on the physicochemical properties, and in vitro testing conditi...

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Detalles Bibliográficos
Autor principal: Kolli, Aditya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651662/
https://www.ncbi.nlm.nih.gov/pubmed/37605430
http://dx.doi.org/10.1111/cts.13616