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Improvements during long-term fasting in patients with long COVID – a case series and literature review
BACKGROUND: Post-acute sequelae of a severe acute respiratory syndrome coronavirus 2 infection, also known as long COVID, comprises a variety of symptoms that impair the quality of life. This represents a growing public health burden, with millions of individuals worldwide affected. CASE DESCRIPTION...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651743/ https://www.ncbi.nlm.nih.gov/pubmed/38024352 http://dx.doi.org/10.3389/fnut.2023.1195270 |
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author | Grundler, Franziska Mesnage, Robin Cerrada, Alberto Wilhelmi de Toledo, Françoise |
author_facet | Grundler, Franziska Mesnage, Robin Cerrada, Alberto Wilhelmi de Toledo, Françoise |
author_sort | Grundler, Franziska |
collection | PubMed |
description | BACKGROUND: Post-acute sequelae of a severe acute respiratory syndrome coronavirus 2 infection, also known as long COVID, comprises a variety of symptoms that impair the quality of life. This represents a growing public health burden, with millions of individuals worldwide affected. CASE DESCRIPTION: We present a case series of 14 COVID-19 patients with post-acute symptoms who underwent medically supervised long-term fasting (6 to 16 days) according to the peer-reviewed Buchinger Wilhelmi protocol. The EQ-5D-5L questionnaire and visual scales were used to evaluate the intensity of the symptoms, retrospectively during the acute phase, and prospectively before and after long-term fasting. Blood tests were also performed before and after fasting. Thirteen patients reported that fasting caused an enhancement in their perceived overall health. Only one patient had no improvement. Both frequent (fatigue, breathlessness, muscle and joint pains) and less frequent (cognitive impairment, smell and taste disorders) sequelae ameliorated. Body weight and other risk factors for cardiometabolic diseases like blood pressure, blood glucose, total cholesterol, low-density-lipoprotein cholesterol, and triglycerides were reduced. No severe side effects occurred. DISCUSSION: This case series reports beneficial changes in self-perceived symptoms in patients with long COVID after long-term fasting. This highlights the potential of long-term fasting as an effective intervention for managing and treating long COVID. |
format | Online Article Text |
id | pubmed-10651743 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106517432023-01-01 Improvements during long-term fasting in patients with long COVID – a case series and literature review Grundler, Franziska Mesnage, Robin Cerrada, Alberto Wilhelmi de Toledo, Françoise Front Nutr Nutrition BACKGROUND: Post-acute sequelae of a severe acute respiratory syndrome coronavirus 2 infection, also known as long COVID, comprises a variety of symptoms that impair the quality of life. This represents a growing public health burden, with millions of individuals worldwide affected. CASE DESCRIPTION: We present a case series of 14 COVID-19 patients with post-acute symptoms who underwent medically supervised long-term fasting (6 to 16 days) according to the peer-reviewed Buchinger Wilhelmi protocol. The EQ-5D-5L questionnaire and visual scales were used to evaluate the intensity of the symptoms, retrospectively during the acute phase, and prospectively before and after long-term fasting. Blood tests were also performed before and after fasting. Thirteen patients reported that fasting caused an enhancement in their perceived overall health. Only one patient had no improvement. Both frequent (fatigue, breathlessness, muscle and joint pains) and less frequent (cognitive impairment, smell and taste disorders) sequelae ameliorated. Body weight and other risk factors for cardiometabolic diseases like blood pressure, blood glucose, total cholesterol, low-density-lipoprotein cholesterol, and triglycerides were reduced. No severe side effects occurred. DISCUSSION: This case series reports beneficial changes in self-perceived symptoms in patients with long COVID after long-term fasting. This highlights the potential of long-term fasting as an effective intervention for managing and treating long COVID. Frontiers Media S.A. 2023-11-02 /pmc/articles/PMC10651743/ /pubmed/38024352 http://dx.doi.org/10.3389/fnut.2023.1195270 Text en Copyright © 2023 Grundler, Mesnage, Cerrada and Wilhelmi de Toledo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Grundler, Franziska Mesnage, Robin Cerrada, Alberto Wilhelmi de Toledo, Françoise Improvements during long-term fasting in patients with long COVID – a case series and literature review |
title | Improvements during long-term fasting in patients with long COVID – a case series and literature review |
title_full | Improvements during long-term fasting in patients with long COVID – a case series and literature review |
title_fullStr | Improvements during long-term fasting in patients with long COVID – a case series and literature review |
title_full_unstemmed | Improvements during long-term fasting in patients with long COVID – a case series and literature review |
title_short | Improvements during long-term fasting in patients with long COVID – a case series and literature review |
title_sort | improvements during long-term fasting in patients with long covid – a case series and literature review |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651743/ https://www.ncbi.nlm.nih.gov/pubmed/38024352 http://dx.doi.org/10.3389/fnut.2023.1195270 |
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