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Genome-edited allogeneic donor “universal” chimeric antigen receptor T cells
αβ T cell receptor (TCRαβ) T cells modified to express chimeric antigen receptors (CAR), are now available as authorized therapies for certain B-cell malignancies. However the process of autologous harvest and generation of patient-specific products is costly, with complex logistics and infrastructu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society of Hematology
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651779/ https://www.ncbi.nlm.nih.gov/pubmed/36223560 http://dx.doi.org/10.1182/blood.2022016204 |