Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is a T-cell malignancy characterized by cell subsets and enriched with leukemia-initiating cells (LICs). β-Catenin modulates LIC activity in T-ALL. However, its role in maintaining established leukemia stem cells remains largely unknown. To identify functi...

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Detalles Bibliográficos
Autores principales: Panelli, Patrizio, De Santis, Elisabetta, Colucci, Mattia, Tamiro, Francesco, Sansico, Francesca, Miroballo, Mattia, Murgo, Emanuele, Padovano, Costanzo, Gusscott, Sam, Ciavarella, Michele, Chavez, Elizabeth A., Bianchi, Fabrizio, Rossi, Giovanni, Carella, Angelo M., Steidl, Christian, Weng, Andrew P., Giambra, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651788/
https://www.ncbi.nlm.nih.gov/pubmed/36315912
http://dx.doi.org/10.1182/blood.2022017079

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