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C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse
Extramedullary infiltration (EMI) is a concomitant manifestation that may indicate poor outcome of acute myeloid leukemia (AML). The underlying mechanism remains poorly understood and therapeutic options are limited. Here, we employed single-cell RNA sequencing on bone marrow (BM) and EMI samples fr...
Autores principales: | Yang, Li-Xue, Zhang, Cheng-Tao, Yang, Meng-Ying, Zhang, Xue-Hong, Liu, Hong-Chen, Luo, Chen-Hui, Jiang, Yue, Wang, Zhang-Man, Yang, Zhong-Yin, Shi, Zhao-Peng, Yang, Yi-Ci, Wei, Ruo-Qu, Zhou, Li, Mi, Jun, Zhou, Ai-Wu, Yao, Zhi-Rong, Xia, Li, Yan, Jin-Song, Lu, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651790/ https://www.ncbi.nlm.nih.gov/pubmed/36322939 http://dx.doi.org/10.1182/blood.2022017046 |
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