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C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse

Extramedullary infiltration (EMI) is a concomitant manifestation that may indicate poor outcome of acute myeloid leukemia (AML). The underlying mechanism remains poorly understood and therapeutic options are limited. Here, we employed single-cell RNA sequencing on bone marrow (BM) and EMI samples fr...

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Detalles Bibliográficos
Autores principales: Yang, Li-Xue, Zhang, Cheng-Tao, Yang, Meng-Ying, Zhang, Xue-Hong, Liu, Hong-Chen, Luo, Chen-Hui, Jiang, Yue, Wang, Zhang-Man, Yang, Zhong-Yin, Shi, Zhao-Peng, Yang, Yi-Ci, Wei, Ruo-Qu, Zhou, Li, Mi, Jun, Zhou, Ai-Wu, Yao, Zhi-Rong, Xia, Li, Yan, Jin-Song, Lu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651790/
https://www.ncbi.nlm.nih.gov/pubmed/36322939
http://dx.doi.org/10.1182/blood.2022017046

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