PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors

Fusion-positive rhabdomyosarcoma (FP-RMS) driven by the expression of the PAX3-FOXO1 (P3F) fusion oncoprotein is an aggressive subtype of pediatric rhabdomyosarcoma. FP-RMS histologically resembles developing muscle yet occurs throughout the body in areas devoid of skeletal muscle highlighting that...

Descripción completa

Detalles Bibliográficos
Autores principales: Searcy, Madeline B., Larsen, Randolph K., Stevens, Bradley T., Zhang, Yang, Jin, Hongjian, Drummond, Catherine J., Langdon, Casey G., Gadek, Katherine E., Vuong, Kyna, Reed, Kristin B., Garcia, Matthew R., Xu, Beisi, Kimbrough, Darden W., Adkins, Grace E., Djekidel, Nadhir, Porter, Shaina N., Schreiner, Patrick A., Pruett-Miller, Shondra M., Abraham, Brian J., Rehg, Jerold E., Hatley, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651858/
https://www.ncbi.nlm.nih.gov/pubmed/37968277
http://dx.doi.org/10.1038/s41467-023-43044-1

Ejemplares similares

Ejemplares similares