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BRISC is required for optimal activation of NF-κB in Kupffer cells induced by LPS and contributes to acute liver injury

BRISC (BRCC3 isopeptidase complex) is a deubiquitinating enzyme that has been linked with inflammatory processes, but its role in liver diseases and the underlying mechanism are unknown. Here, we investigated the pathophysiological role of BRISC in acute liver failure using a mice model induced by D...

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Detalles Bibliográficos
Autores principales:	Zhang, Wen, Liu, Kai, Ren, Guang-Ming, Wang, Yu, Wang, Ting, Liu, Xian, Li, Dong-Xu, Xiao, Yang, Chen, Xu, Li, Ya-Ting, Zhan, Yi-Qun, Xiang, Shen-Si, Chen, Hui, Gao, Hui-Ying, Zhao, Ke, Yu, Miao, Ge, Chang-Hui, Li, Chang-Yan, Ge, Zhi-Qiang, Yang, Xiao-Ming, Yin, Rong-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10651896/ https://www.ncbi.nlm.nih.gov/pubmed/37968261 http://dx.doi.org/10.1038/s41419-023-06268-z

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