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Interferon stimulated immune profile changes in a humanized mouse model of HBV infection

The underlying mechanism of chronic hepatitis B virus (HBV) functional cure by interferon (IFN), especially in patients with low HBsAg and/or young ages, is still unresolved due to the lack of surrogate models. Here, we generate a type I interferon receptor humanized mouse (huIFNAR mouse) through a...

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Detalles Bibliográficos
Autores principales:	Wang, Yaping, Guo, Liliangzi, Shi, Jingrong, Li, Jingyun, Wen, Yanling, Gu, Guoming, Cui, Jianping, Feng, Chengqian, Jiang, Mengling, Fan, Qinghong, Tang, Jingyan, Chen, Sisi, Zhang, Jun, Zheng, Xiaowen, Pan, Meifang, Li, Xinnian, Sun, Yanxia, Zhang, Zheng, Li, Xian, Hu, Fengyu, Zhang, Liguo, Tang, Xiaoping, Li, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652013/ https://www.ncbi.nlm.nih.gov/pubmed/37968364 http://dx.doi.org/10.1038/s41467-023-43078-5

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