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Crosstalk between the tRNA methyltransferase Trm1 and RNA chaperone La influences eukaryotic tRNA maturation

tRNAs undergo an extensive maturation process involving posttranscriptional modifications often associated with tRNA structural stability and promoting the native fold. Impaired posttranscriptional modification has been linked to human disease, likely through defects in translation, mitochondrial fu...

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Detalles Bibliográficos
Autores principales: Porat, Jennifer, Vakiloroayaei, Ana, Remnant, Brittney M., Talebi, Mohammadaref, Cargill, Taylor, Bayfield, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652106/
https://www.ncbi.nlm.nih.gov/pubmed/37805140
http://dx.doi.org/10.1016/j.jbc.2023.105326

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