The mutations on the envelope glycoprotein D contribute to the enhanced neurotropism of the pseudorabies virus variant

The pseudorabies virus (PRV) TJ strain, a variant of PRV, induces more severe neurological symptoms and higher mortality in piglets and mice than the PRV SC strain isolated in 1980. However, the mechanism underlying responsible for the discrepancy in virulence between these strains remains unclear....

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Detalles Bibliográficos
Autores principales: Wu, Hongxia, Qi, Hansong, Wang, Bing, Li, Mingzhi, Qu, Liang, Li, Su, Luo, Yuzi, Li, Lian-Feng, Zheng, Guang-Lai, Qiu, Hua-Ji, Sun, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652121/
https://www.ncbi.nlm.nih.gov/pubmed/37838171
http://dx.doi.org/10.1016/j.jbc.2023.105347

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