A cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin

Previous genome-wide association studies (GWASs) for adiponectin, a complex trait linked to type 2 diabetes and obesity, identified >20 associated loci. However, most loci were identified in populations of European ancestry, and many of the target genes underlying the associations remain unknown....

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Detalles Bibliográficos
Autores principales: Sarsani, Vishal, Brotman, Sarah M., Xianyong, Yin, Fernandes Silva, Lillian, Laakso, Markku, Spracklen, Cassandra N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652123/
https://www.ncbi.nlm.nih.gov/pubmed/37859345
http://dx.doi.org/10.1016/j.xhgg.2023.100252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652123/
https://www.ncbi.nlm.nih.gov/pubmed/37859345
http://dx.doi.org/10.1016/j.xhgg.2023.100252

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