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A cross-ancestry genome-wide meta-analysis, fine-mapping, and gene prioritization approach to characterize the genetic architecture of adiponectin
Previous genome-wide association studies (GWASs) for adiponectin, a complex trait linked to type 2 diabetes and obesity, identified >20 associated loci. However, most loci were identified in populations of European ancestry, and many of the target genes underlying the associations remain unknown....
Autores principales: | Sarsani, Vishal, Brotman, Sarah M., Xianyong, Yin, Fernandes Silva, Lillian, Laakso, Markku, Spracklen, Cassandra N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652123/ https://www.ncbi.nlm.nih.gov/pubmed/37859345 http://dx.doi.org/10.1016/j.xhgg.2023.100252 |
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