Cargando…

Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic

BACKGROUND: To define changes in AMI case rates, patient demographics, cardiovascular comorbidities, treatment approaches, in-hospital outcomes, and the economic burden of COVID-19 during the pandemic. METHODS: We conducted a multicenter, observational survey with selected hospitals from three medic...

Descripción completa

Detalles Bibliográficos
Autores principales: Pourasghari, Hamid, Kolivand, Pirhossein, Azari, Samad, Saberian, Peyman, Behzadifar, Masoud, Omidi, Negar, Salehbeigi, Shahrzad, Raei, Behzad, Rajaie, Soheila, Luigi Bragazzi, Nicola, Golpira, Reza, Khorgami, Mohammd Rafie, Khani, Mohammad, Montazerinamin, Sara, Lotfi, Farhad, Tajdini, Masih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652134/
https://www.ncbi.nlm.nih.gov/pubmed/38020058
http://dx.doi.org/10.1016/j.ijcha.2023.101288
_version_ 1785136144604725248
author Pourasghari, Hamid
Kolivand, Pirhossein
Azari, Samad
Saberian, Peyman
Behzadifar, Masoud
Omidi, Negar
Salehbeigi, Shahrzad
Raei, Behzad
Rajaie, Soheila
Luigi Bragazzi, Nicola
Golpira, Reza
Khorgami, Mohammd Rafie
Khani, Mohammad
Montazerinamin, Sara
Lotfi, Farhad
Tajdini, Masih
author_facet Pourasghari, Hamid
Kolivand, Pirhossein
Azari, Samad
Saberian, Peyman
Behzadifar, Masoud
Omidi, Negar
Salehbeigi, Shahrzad
Raei, Behzad
Rajaie, Soheila
Luigi Bragazzi, Nicola
Golpira, Reza
Khorgami, Mohammd Rafie
Khani, Mohammad
Montazerinamin, Sara
Lotfi, Farhad
Tajdini, Masih
author_sort Pourasghari, Hamid
collection PubMed
description BACKGROUND: To define changes in AMI case rates, patient demographics, cardiovascular comorbidities, treatment approaches, in-hospital outcomes, and the economic burden of COVID-19 during the pandemic. METHODS: We conducted a multicenter, observational survey with selected hospitals from three medical universities in Tehran city. A data collection tool consisting of three parts. The first part included socio-demographic information, and the second part included clinical information, major complications, and in-hospital mortality. Finally, the third part was related to the direct medical costs generated by AMI in COVID-19 and non-COVID-19 patients. The study cohort comprised 4,560 hospitalizations for AMI (2,935 for STEMI [64%] and 1,625 for NSTEMI [36%]). RESULTS: Of those hospitalized for AMI, 1,864 (76.6 %) and 1,659 (78 %) were male before the COVID-19 outbreak and during the COVID-19 era, respectively. The length of stay (LOS), was significantly lower during the COVID-19 pandemic era (4.27 ± 3.63 vs 5.24 ± 5.17, p = 0.00). Results showed that there were no significant differences in terms of patient risk factors across periods. A total of 2,126 AMIs were registered during the COVID-19 era, with a 12.65 % reduction (95 % CI 1.5–25.1) compared with the equivalent time in 2019 (P = 0.179). The risk of in-hospital mortality rate for AMI patients increased from 4.9 % in 2019 to 7.0 % in the COVID-19 era (OR = 1.42; 95 % CI 1.11–1.82; P = 0.004). Major complications were registered in 9.7 % of cases in 2020, which is higher than the rate of 6.6 % reported in 2019 (OR = 1.46, 95 % CI 1.11–1.82; P = 0.000). Total costs in hospitalized AMI-COVID patients averaged $188 more than in AMI patients (P = 0.020). CONCLUSION: This cross-sectional study found important changes in AMI hospitalization rates, worse outcomes, and higher costs during the COVID-19 periods. Future studies are recommended to examine the long-term outcomes of hospitalized AMI patients during the COVID-19 era.
format Online
Article
Text
id pubmed-10652134
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-106521342023-11-04 Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic Pourasghari, Hamid Kolivand, Pirhossein Azari, Samad Saberian, Peyman Behzadifar, Masoud Omidi, Negar Salehbeigi, Shahrzad Raei, Behzad Rajaie, Soheila Luigi Bragazzi, Nicola Golpira, Reza Khorgami, Mohammd Rafie Khani, Mohammad Montazerinamin, Sara Lotfi, Farhad Tajdini, Masih Int J Cardiol Heart Vasc Original Paper BACKGROUND: To define changes in AMI case rates, patient demographics, cardiovascular comorbidities, treatment approaches, in-hospital outcomes, and the economic burden of COVID-19 during the pandemic. METHODS: We conducted a multicenter, observational survey with selected hospitals from three medical universities in Tehran city. A data collection tool consisting of three parts. The first part included socio-demographic information, and the second part included clinical information, major complications, and in-hospital mortality. Finally, the third part was related to the direct medical costs generated by AMI in COVID-19 and non-COVID-19 patients. The study cohort comprised 4,560 hospitalizations for AMI (2,935 for STEMI [64%] and 1,625 for NSTEMI [36%]). RESULTS: Of those hospitalized for AMI, 1,864 (76.6 %) and 1,659 (78 %) were male before the COVID-19 outbreak and during the COVID-19 era, respectively. The length of stay (LOS), was significantly lower during the COVID-19 pandemic era (4.27 ± 3.63 vs 5.24 ± 5.17, p = 0.00). Results showed that there were no significant differences in terms of patient risk factors across periods. A total of 2,126 AMIs were registered during the COVID-19 era, with a 12.65 % reduction (95 % CI 1.5–25.1) compared with the equivalent time in 2019 (P = 0.179). The risk of in-hospital mortality rate for AMI patients increased from 4.9 % in 2019 to 7.0 % in the COVID-19 era (OR = 1.42; 95 % CI 1.11–1.82; P = 0.004). Major complications were registered in 9.7 % of cases in 2020, which is higher than the rate of 6.6 % reported in 2019 (OR = 1.46, 95 % CI 1.11–1.82; P = 0.000). Total costs in hospitalized AMI-COVID patients averaged $188 more than in AMI patients (P = 0.020). CONCLUSION: This cross-sectional study found important changes in AMI hospitalization rates, worse outcomes, and higher costs during the COVID-19 periods. Future studies are recommended to examine the long-term outcomes of hospitalized AMI patients during the COVID-19 era. Elsevier 2023-11-04 /pmc/articles/PMC10652134/ /pubmed/38020058 http://dx.doi.org/10.1016/j.ijcha.2023.101288 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Paper
Pourasghari, Hamid
Kolivand, Pirhossein
Azari, Samad
Saberian, Peyman
Behzadifar, Masoud
Omidi, Negar
Salehbeigi, Shahrzad
Raei, Behzad
Rajaie, Soheila
Luigi Bragazzi, Nicola
Golpira, Reza
Khorgami, Mohammd Rafie
Khani, Mohammad
Montazerinamin, Sara
Lotfi, Farhad
Tajdini, Masih
Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
title Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
title_full Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
title_fullStr Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
title_full_unstemmed Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
title_short Epidemiological, clinical, and economic burden of myocardial infarction patients in Iran during the COVID-19 pandemic
title_sort epidemiological, clinical, and economic burden of myocardial infarction patients in iran during the covid-19 pandemic
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652134/
https://www.ncbi.nlm.nih.gov/pubmed/38020058
http://dx.doi.org/10.1016/j.ijcha.2023.101288
work_keys_str_mv AT pourasgharihamid epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT kolivandpirhossein epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT azarisamad epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT saberianpeyman epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT behzadifarmasoud epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT omidinegar epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT salehbeigishahrzad epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT raeibehzad epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT rajaiesoheila epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT luigibragazzinicola epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT golpirareza epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT khorgamimohammdrafie epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT khanimohammad epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT montazerinaminsara epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT lotfifarhad epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic
AT tajdinimasih epidemiologicalclinicalandeconomicburdenofmyocardialinfarctionpatientsiniranduringthecovid19pandemic