Pharmacologic Inhibition of Myostatin With a Myostatin Antibody Improves the Skeletal Muscle and Bone Phenotype of Male Insulin‐Deficient Diabetic Mice

Type 1 diabetes (T1D) is associated with low bone and muscle mass, increased fracture risk, and impaired skeletal muscle function. Myostatin, a myokine that is systemically elevated in humans with T1D, negatively regulates muscle mass and bone formation. We investigated whether pharmacologic myostat...

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Detalles Bibliográficos
Autores principales: Bunn, R Clay, Adatorwovor, Reuben, Smith, Rebecca R, Ray, Philip D, Fields, Sarah E, Keeble, Alexander R, Fry, Christopher S, Uppuganti, Sasidhar, Nyman, Jeffry S, Fowlkes, John L, Kalaitzoglou, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652179/
https://www.ncbi.nlm.nih.gov/pubmed/38025035
http://dx.doi.org/10.1002/jbm4.10833

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