Acute irradiation causes a long-term disturbance in the heterogeneity and gene expression profile of medullary thymic epithelial cells

The thymus has the ability to regenerate from acute injury caused by radiation, infection, and stressors. In addition to thymocytes, thymic epithelial cells in the medulla (mTECs), which are crucial for T cell self-tolerance by ectopically expressing and presenting thousands of tissue-specific antig...

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Detalles Bibliográficos
Autores principales: Horie, Kenta, Namiki, Kano, Kinoshita, Kyouhei, Miyauchi, Maki, Ishikawa, Tatsuya, Hayama, Mio, Maruyama, Yuya, Hagiwara, Naho, Miyao, Takahisa, Murata, Shigeo, Kobayashi, Tetsuya J., Akiyama, Nobuko, Akiyama, Taishin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652284/
https://www.ncbi.nlm.nih.gov/pubmed/38022666
http://dx.doi.org/10.3389/fimmu.2023.1186154

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