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Senolytic treatment reduces oxidative protein stress in an aging male murine model of post‐traumatic osteoarthritis
Senolytic drugs are designed to selectively clear senescent cells (SnCs) that accumulate with injury or aging. In a mouse model of osteoarthritis (OA), senolysis yields a pro‐regenerative response, but the therapeutic benefit is reduced in aged mice. Increased oxidative stress is a hallmark of advan...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652304/ https://www.ncbi.nlm.nih.gov/pubmed/37749958 http://dx.doi.org/10.1111/acel.13979 |