Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates

[Image: see text] Fuchs’ corneal endothelial dystrophy (FECD) is a major cause of vision loss. Corneal transplantation is the only effective curative treatment, but this surgery has limitations. A pharmacological intervention would complement surgery and be beneficial for many patients. FECD is caus...

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Detalles Bibliográficos
Autores principales: Hu, Jiaxin, Shen, Xiulong, Kheirabadi, Mahboubeh, Streeter, Matthew D., Qian, Ziqing, Mootha, V. Vinod, Corey, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652360/
https://www.ncbi.nlm.nih.gov/pubmed/38024683
http://dx.doi.org/10.1021/acsomega.3c05634

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