Novel Kinetic Resolution of Thiazolo-Benzimidazolines Using MAO Enzymes

[Image: see text] The kinetic resolution of racemic 1H,3H-thiazolo[3,4-a]benzimidazoline (TBIM) heterocycles was achieved using E. coli whole cells expressing the MAO-N D11 enzyme. Several cosolvents were screened using TBIM 2a as the substrate. DMF was the best cosolvent, affording the pure enantio...

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Detalles Bibliográficos
Autores principales: Villamil, Valentina, Vairoletti, Franco, Tijman, Ariel, López, Gonzalo, Peixoto de Abreu Lima, Alejandro, Saiz, Cecilia, Iglesias, César, Mahler, Graciela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652373/
https://www.ncbi.nlm.nih.gov/pubmed/38024698
http://dx.doi.org/10.1021/acsomega.3c03223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652373/
https://www.ncbi.nlm.nih.gov/pubmed/38024698
http://dx.doi.org/10.1021/acsomega.3c03223

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