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Novel Kinetic Resolution of Thiazolo-Benzimidazolines Using MAO Enzymes
[Image: see text] The kinetic resolution of racemic 1H,3H-thiazolo[3,4-a]benzimidazoline (TBIM) heterocycles was achieved using E. coli whole cells expressing the MAO-N D11 enzyme. Several cosolvents were screened using TBIM 2a as the substrate. DMF was the best cosolvent, affording the pure enantio...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652373/ https://www.ncbi.nlm.nih.gov/pubmed/38024698 http://dx.doi.org/10.1021/acsomega.3c03223 |