Apoptosis mechanisms induced by 15d-PMJ(2) in HCT116 colon cancer cells: insights into CHOP10/TRB3/Akt signaling

Agents that stimulate the endoplasmic reticulum (ER) stress pathway are being exploited pharmacologically to induce cancer cell death. Cytotoxic ER stress is typically regulated by the transcription factor, C/EBP homologous protein 10 (CHOP10). Products of CHOP10 transcription include the pro-apopto...

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Detalles Bibliográficos
Autores principales: Albassam, Hussam, Ladin, Daniel A., Elhassanny, Ahmed, Burns, Colin, Van Dross-Anderson, Rukiyah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652392/
https://www.ncbi.nlm.nih.gov/pubmed/38026967
http://dx.doi.org/10.3389/fphar.2023.1283677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652392/
https://www.ncbi.nlm.nih.gov/pubmed/38026967
http://dx.doi.org/10.3389/fphar.2023.1283677

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