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Apoptosis mechanisms induced by 15d-PMJ(2) in HCT116 colon cancer cells: insights into CHOP10/TRB3/Akt signaling

Agents that stimulate the endoplasmic reticulum (ER) stress pathway are being exploited pharmacologically to induce cancer cell death. Cytotoxic ER stress is typically regulated by the transcription factor, C/EBP homologous protein 10 (CHOP10). Products of CHOP10 transcription include the pro-apopto...

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Detalles Bibliográficos
Autores principales:	Albassam, Hussam, Ladin, Daniel A., Elhassanny, Ahmed, Burns, Colin, Van Dross-Anderson, Rukiyah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652392/ https://www.ncbi.nlm.nih.gov/pubmed/38026967 http://dx.doi.org/10.3389/fphar.2023.1283677

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