Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are related neurodegenerative diseases that belong to a common disease spectrum based on overlapping clinical, pathological and genetic evidence. Early pathological changes to the morphology and synapses of affected neuron populat...

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Detalles Bibliográficos
Autores principales: Pelaez, Mari Carmen, Desmeules, Antoine, Gelon, Pauline A., Glasson, Bastien, Marcadet, Laetitia, Rodgers, Alicia, Phaneuf, Daniel, Pozzi, Silvia, Dutchak, Paul A., Julien, Jean-Pierre, Sephton, Chantelle F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652582/
https://www.ncbi.nlm.nih.gov/pubmed/37974279
http://dx.doi.org/10.1186/s40478-023-01671-1

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