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Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome

Women with polycystic ovary syndrome (PCOS) have a high prevalence of metabolic syndrome (MS), with rates up to 33%. This is associated with long-term consequences such as cardiovascular diseases, type 2 diabetes mellitus (T2DM), cancer, sleep apnea, and psychological issues. The prevalence of MS wo...

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Autores principales: Artyomenko, Volodymyr, Velychko, Valentyna, Lahoda, Daria, Danylchuk, Halyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652679/
https://www.ncbi.nlm.nih.gov/pubmed/38024815
http://dx.doi.org/10.25122/jml-2023-0057
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author Artyomenko, Volodymyr
Velychko, Valentyna
Lahoda, Daria
Danylchuk, Halyna
author_facet Artyomenko, Volodymyr
Velychko, Valentyna
Lahoda, Daria
Danylchuk, Halyna
author_sort Artyomenko, Volodymyr
collection PubMed
description Women with polycystic ovary syndrome (PCOS) have a high prevalence of metabolic syndrome (MS), with rates up to 33%. This is associated with long-term consequences such as cardiovascular diseases, type 2 diabetes mellitus (T2DM), cancer, sleep apnea, and psychological issues. The prevalence of MS worldwide is often associated with obesity and T2DM, yet regional variations are reported. In this study, 122 women consulting general practice and family medicine physicians were evaluated, revealing a BMI exceeding 30 kg/m(2). Among MS criteria, the most common diagnoses were T2DM in 29 patients, insulin resistance (IR) in 36, arterial hypertension (AH) in 51, reduced HDL levels in 53, and elevated triglycerides in 39. Further analysis revealed 16 unique combinations of MS components in these patients, with 75% of PCOS cases exhibiting three MS components and 25% having four. Additionally, research indicated that most women with PCOS face persistent, treatment-resistant obesity, with a notably higher BMI (ρ=0.87; r=0.76). These findings highlight the multifactorial nature of PCOS and MS etiology.
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spelling pubmed-106526792023-08-01 Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome Artyomenko, Volodymyr Velychko, Valentyna Lahoda, Daria Danylchuk, Halyna J Med Life Original Article Women with polycystic ovary syndrome (PCOS) have a high prevalence of metabolic syndrome (MS), with rates up to 33%. This is associated with long-term consequences such as cardiovascular diseases, type 2 diabetes mellitus (T2DM), cancer, sleep apnea, and psychological issues. The prevalence of MS worldwide is often associated with obesity and T2DM, yet regional variations are reported. In this study, 122 women consulting general practice and family medicine physicians were evaluated, revealing a BMI exceeding 30 kg/m(2). Among MS criteria, the most common diagnoses were T2DM in 29 patients, insulin resistance (IR) in 36, arterial hypertension (AH) in 51, reduced HDL levels in 53, and elevated triglycerides in 39. Further analysis revealed 16 unique combinations of MS components in these patients, with 75% of PCOS cases exhibiting three MS components and 25% having four. Additionally, research indicated that most women with PCOS face persistent, treatment-resistant obesity, with a notably higher BMI (ρ=0.87; r=0.76). These findings highlight the multifactorial nature of PCOS and MS etiology. Carol Davila University Press 2023-08 /pmc/articles/PMC10652679/ /pubmed/38024815 http://dx.doi.org/10.25122/jml-2023-0057 Text en ©2023 JOURNAL of MEDICINE and LIFE https://creativecommons.org/licenses/by/4.0/This open access article is licensed under Creative Commons Attribution 4.0 International (CC BY 4.0). http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Original Article
Artyomenko, Volodymyr
Velychko, Valentyna
Lahoda, Daria
Danylchuk, Halyna
Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
title Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
title_full Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
title_fullStr Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
title_full_unstemmed Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
title_short Common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
title_sort common clinical laboratory features among women with polycystic ovary syndrome and metabolic syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652679/
https://www.ncbi.nlm.nih.gov/pubmed/38024815
http://dx.doi.org/10.25122/jml-2023-0057
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