Cell-free DNA measurement of three genomes after allogeneic MSC therapy in kidney transplant recipients indicates early cell death of infused MSC

INTRODUCTION: Mesenchymal stromal cell (MSC) therapy is a promising treatment that allows for drug minimization in clinical kidney transplantation. While it is thought that MSCs rapidly go into apoptosis after infusion, clinical evidence for this is scarce since methods to detect cell death of infus...

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Detalles Bibliográficos
Autores principales: Dreyer, Geertje J., Drabbels, Jos JM., de Fijter, Johan W., van Kooten, Cees, Reinders, Marlies EJ., Heidt, Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652747/
https://www.ncbi.nlm.nih.gov/pubmed/38022634
http://dx.doi.org/10.3389/fimmu.2023.1240347

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