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Mathematical Modeling Identifies Optimum Palbociclib-fulvestrant Dose Administration Schedules for the Treatment of Patients with Estrogen Receptor–positive Breast Cancer
Cyclin-dependent kinases 4/6 (CDK4/6) inhibitors such as palbociclib are approved for the treatment of metastatic estrogen receptor–positive (ER(+)) breast cancer in combination with endocrine therapies and significantly improve outcomes in patients with this disease. However, given the large number...
Autores principales: | Cheng, Yu-Chen, Stein, Shayna, Nardone, Agostina, Liu, Weihan, Ma, Wen, Cohen, Gabriella, Guarducci, Cristina, McDonald, Thomas O., Jeselsohn, Rinath, Michor, Franziska |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10652811/ https://www.ncbi.nlm.nih.gov/pubmed/37921419 http://dx.doi.org/10.1158/2767-9764.CRC-23-0257 |
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