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1-Sulfonyl-3-amino-1H-1,2,4-triazoles as Yellow Fever Virus Inhibitors: Synthesis and Structure–Activity Relationship

[Image: see text] Yellow fever virus (YFV) transmitted by infected mosquitoes causes an acute viral disease for which there are no approved small-molecule therapeutics. Our recently developed machine learning models for YFV inhibitors led to the selection of a new pyrazolesulfonamide derivative RCB1...

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Detalles Bibliográficos
Autores principales: Kazakova, Elena, Lane, Thomas R., Jones, Thane, Puhl, Ana C., Riabova, Olga, Makarov, Vadim, Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653066/
https://www.ncbi.nlm.nih.gov/pubmed/38024733
http://dx.doi.org/10.1021/acsomega.3c06106