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Minimal information for reporting a genomics experiment
Exome and genome sequencing has facilitated the identification of hundreds of genes and other regions that are recurrently mutated in hematologic neoplasms. The data sets from these studies theoretically provide opportunities. Quality differences between data sets can confound secondary analyses. We...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653092/ https://www.ncbi.nlm.nih.gov/pubmed/36219881 http://dx.doi.org/10.1182/blood.2022016095 |
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author | Dreval, Kostiantyn Boutros, Paul C. Morin, Ryan D. |
author_facet | Dreval, Kostiantyn Boutros, Paul C. Morin, Ryan D. |
author_sort | Dreval, Kostiantyn |
collection | PubMed |
description | Exome and genome sequencing has facilitated the identification of hundreds of genes and other regions that are recurrently mutated in hematologic neoplasms. The data sets from these studies theoretically provide opportunities. Quality differences between data sets can confound secondary analyses. We explore the consequences of these on the conclusions from some recent studies of B-cell lymphomas. We highlight the need for a minimum reporting standard to increase transparency in genomic research. |
format | Online Article Text |
id | pubmed-10653092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The American Society of Hematology |
record_format | MEDLINE/PubMed |
spelling | pubmed-106530922022-10-14 Minimal information for reporting a genomics experiment Dreval, Kostiantyn Boutros, Paul C. Morin, Ryan D. Blood Blood Spotlight Exome and genome sequencing has facilitated the identification of hundreds of genes and other regions that are recurrently mutated in hematologic neoplasms. The data sets from these studies theoretically provide opportunities. Quality differences between data sets can confound secondary analyses. We explore the consequences of these on the conclusions from some recent studies of B-cell lymphomas. We highlight the need for a minimum reporting standard to increase transparency in genomic research. The American Society of Hematology 2022-12-15 2022-10-14 /pmc/articles/PMC10653092/ /pubmed/36219881 http://dx.doi.org/10.1182/blood.2022016095 Text en © 2022 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution. All other rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Blood Spotlight Dreval, Kostiantyn Boutros, Paul C. Morin, Ryan D. Minimal information for reporting a genomics experiment |
title | Minimal information for reporting a genomics experiment |
title_full | Minimal information for reporting a genomics experiment |
title_fullStr | Minimal information for reporting a genomics experiment |
title_full_unstemmed | Minimal information for reporting a genomics experiment |
title_short | Minimal information for reporting a genomics experiment |
title_sort | minimal information for reporting a genomics experiment |
topic | Blood Spotlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653092/ https://www.ncbi.nlm.nih.gov/pubmed/36219881 http://dx.doi.org/10.1182/blood.2022016095 |
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