S100A8/A9 drives the formation of procoagulant platelets through GPIbα

S100A8/A9, also known as “calprotectin” or “MRP8/14,” is an alarmin primarily secreted by activated myeloid cells with antimicrobial, proinflammatory, and prothrombotic properties. Increased plasma levels of S100A8/A9 in thrombo-inflammatory diseases are associated with thrombotic complications. We...

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Detalles Bibliográficos
Autores principales: Colicchia, Martina, Schrottmaier, Waltraud C., Perrella, Gina, Reyat, Jasmeet S., Begum, Jenefa, Slater, Alexandre, Price, Joshua, Clark, Joanne C., Zhi, Zhaogong, Simpson, Megan J., Bourne, Joshua H., Poulter, Natalie S., Khan, Abdullah O., Nicolson, Phillip L. R., Pugh, Matthew, Harrison, Paul, Iqbal, Asif J., Rainger, George E., Watson, Steve P., Thomas, Mark R., Mutch, Nicola J., Assinger, Alice, Rayes, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653093/
https://www.ncbi.nlm.nih.gov/pubmed/36026606
http://dx.doi.org/10.1182/blood.2021014966

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