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Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653417/ https://www.ncbi.nlm.nih.gov/pubmed/37972032 http://dx.doi.org/10.1371/journal.pone.0289809 |
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author | Habibu, Buhari Aluwong, Tagang Yaqub, Lukuman Surakat Buhari, Hajarah Uwale Makun, Hussaina Joan Kawu, Mohammed Umaru |
author_facet | Habibu, Buhari Aluwong, Tagang Yaqub, Lukuman Surakat Buhari, Hajarah Uwale Makun, Hussaina Joan Kawu, Mohammed Umaru |
author_sort | Habibu, Buhari |
collection | PubMed |
description | The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids were recorded at birth and blood samples were collected from the dwarf and normal-sized (Red Sokoto and Sahel) goats on Days 0 (birth), 3, 10 and 20, postnatal. Also, the body mass index (BMI) was calculated and the concentration of metabolic markers was determined. Results revealed that values of BMI, body weight, length and height were lowest (P < 0.01) in the dwarf, followed by values in Red Sokoto kids, while the Sahel kids had the highest (P < 0.01) values. Conversely, the concentration of triglyceride at birth was highest (P < 0.05) in the dwarf, moderate in Red Sokoto and lowest in Sahel goats. Similarly, the Sahel goat kids had the lowest neonatal (P < 0.05) concentration of serum cholesterol. Neonatal concentrations of serum albumin and urea were higher in Sahel than Red Sokoto (P < 0.05) and the dwarf (P > 0.05) goats. Concentration of serum albumin was lower (P < 0.05) at birth, but significantly increased later, while values of serum urea concentration were higher (P < 0.05) at birth, but significantly decreased in subsequent postnatal days. Unlike the BMI, birth weight showed significant negative (P < 0.05) correlation with the concentration of most serum metabolites, especially triglyceride, which showed negative correlation at birth and in subsequent postnatal days. We concluded that dwarfism or small body size is associated with high serum triglyceride in single-born neonatal goats, and this is probably due to the accumulation of body energy reserve in the form of body fat to compensate for lower body tissue mass. |
format | Online Article Text |
id | pubmed-10653417 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-106534172023-11-16 Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size Habibu, Buhari Aluwong, Tagang Yaqub, Lukuman Surakat Buhari, Hajarah Uwale Makun, Hussaina Joan Kawu, Mohammed Umaru PLoS One Research Article The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids were recorded at birth and blood samples were collected from the dwarf and normal-sized (Red Sokoto and Sahel) goats on Days 0 (birth), 3, 10 and 20, postnatal. Also, the body mass index (BMI) was calculated and the concentration of metabolic markers was determined. Results revealed that values of BMI, body weight, length and height were lowest (P < 0.01) in the dwarf, followed by values in Red Sokoto kids, while the Sahel kids had the highest (P < 0.01) values. Conversely, the concentration of triglyceride at birth was highest (P < 0.05) in the dwarf, moderate in Red Sokoto and lowest in Sahel goats. Similarly, the Sahel goat kids had the lowest neonatal (P < 0.05) concentration of serum cholesterol. Neonatal concentrations of serum albumin and urea were higher in Sahel than Red Sokoto (P < 0.05) and the dwarf (P > 0.05) goats. Concentration of serum albumin was lower (P < 0.05) at birth, but significantly increased later, while values of serum urea concentration were higher (P < 0.05) at birth, but significantly decreased in subsequent postnatal days. Unlike the BMI, birth weight showed significant negative (P < 0.05) correlation with the concentration of most serum metabolites, especially triglyceride, which showed negative correlation at birth and in subsequent postnatal days. We concluded that dwarfism or small body size is associated with high serum triglyceride in single-born neonatal goats, and this is probably due to the accumulation of body energy reserve in the form of body fat to compensate for lower body tissue mass. Public Library of Science 2023-11-16 /pmc/articles/PMC10653417/ /pubmed/37972032 http://dx.doi.org/10.1371/journal.pone.0289809 Text en © 2023 Habibu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Habibu, Buhari Aluwong, Tagang Yaqub, Lukuman Surakat Buhari, Hajarah Uwale Makun, Hussaina Joan Kawu, Mohammed Umaru Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size |
title | Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size |
title_full | Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size |
title_fullStr | Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size |
title_full_unstemmed | Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size |
title_short | Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size |
title_sort | metabolic adjustments in neonatal dwarf and normal-sized goat kids: relationship between serum metabolites and body size |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653417/ https://www.ncbi.nlm.nih.gov/pubmed/37972032 http://dx.doi.org/10.1371/journal.pone.0289809 |
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