Cargando…

Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size

The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids...

Descripción completa

Detalles Bibliográficos
Autores principales: Habibu, Buhari, Aluwong, Tagang, Yaqub, Lukuman Surakat, Buhari, Hajarah Uwale, Makun, Hussaina Joan, Kawu, Mohammed Umaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653417/
https://www.ncbi.nlm.nih.gov/pubmed/37972032
http://dx.doi.org/10.1371/journal.pone.0289809
_version_ 1785147772549201920
author Habibu, Buhari
Aluwong, Tagang
Yaqub, Lukuman Surakat
Buhari, Hajarah Uwale
Makun, Hussaina Joan
Kawu, Mohammed Umaru
author_facet Habibu, Buhari
Aluwong, Tagang
Yaqub, Lukuman Surakat
Buhari, Hajarah Uwale
Makun, Hussaina Joan
Kawu, Mohammed Umaru
author_sort Habibu, Buhari
collection PubMed
description The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids were recorded at birth and blood samples were collected from the dwarf and normal-sized (Red Sokoto and Sahel) goats on Days 0 (birth), 3, 10 and 20, postnatal. Also, the body mass index (BMI) was calculated and the concentration of metabolic markers was determined. Results revealed that values of BMI, body weight, length and height were lowest (P < 0.01) in the dwarf, followed by values in Red Sokoto kids, while the Sahel kids had the highest (P < 0.01) values. Conversely, the concentration of triglyceride at birth was highest (P < 0.05) in the dwarf, moderate in Red Sokoto and lowest in Sahel goats. Similarly, the Sahel goat kids had the lowest neonatal (P < 0.05) concentration of serum cholesterol. Neonatal concentrations of serum albumin and urea were higher in Sahel than Red Sokoto (P < 0.05) and the dwarf (P > 0.05) goats. Concentration of serum albumin was lower (P < 0.05) at birth, but significantly increased later, while values of serum urea concentration were higher (P < 0.05) at birth, but significantly decreased in subsequent postnatal days. Unlike the BMI, birth weight showed significant negative (P < 0.05) correlation with the concentration of most serum metabolites, especially triglyceride, which showed negative correlation at birth and in subsequent postnatal days. We concluded that dwarfism or small body size is associated with high serum triglyceride in single-born neonatal goats, and this is probably due to the accumulation of body energy reserve in the form of body fat to compensate for lower body tissue mass.
format Online
Article
Text
id pubmed-10653417
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-106534172023-11-16 Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size Habibu, Buhari Aluwong, Tagang Yaqub, Lukuman Surakat Buhari, Hajarah Uwale Makun, Hussaina Joan Kawu, Mohammed Umaru PLoS One Research Article The relationship between body size and metabolism of goats remains poorly studied. The study evaluated the neonatal metabolic adjustments and elucidated the relationship between serum metabolites and body size in 39 single-born dwarf and normal-sized goat kids. Body weight, length and height of kids were recorded at birth and blood samples were collected from the dwarf and normal-sized (Red Sokoto and Sahel) goats on Days 0 (birth), 3, 10 and 20, postnatal. Also, the body mass index (BMI) was calculated and the concentration of metabolic markers was determined. Results revealed that values of BMI, body weight, length and height were lowest (P < 0.01) in the dwarf, followed by values in Red Sokoto kids, while the Sahel kids had the highest (P < 0.01) values. Conversely, the concentration of triglyceride at birth was highest (P < 0.05) in the dwarf, moderate in Red Sokoto and lowest in Sahel goats. Similarly, the Sahel goat kids had the lowest neonatal (P < 0.05) concentration of serum cholesterol. Neonatal concentrations of serum albumin and urea were higher in Sahel than Red Sokoto (P < 0.05) and the dwarf (P > 0.05) goats. Concentration of serum albumin was lower (P < 0.05) at birth, but significantly increased later, while values of serum urea concentration were higher (P < 0.05) at birth, but significantly decreased in subsequent postnatal days. Unlike the BMI, birth weight showed significant negative (P < 0.05) correlation with the concentration of most serum metabolites, especially triglyceride, which showed negative correlation at birth and in subsequent postnatal days. We concluded that dwarfism or small body size is associated with high serum triglyceride in single-born neonatal goats, and this is probably due to the accumulation of body energy reserve in the form of body fat to compensate for lower body tissue mass. Public Library of Science 2023-11-16 /pmc/articles/PMC10653417/ /pubmed/37972032 http://dx.doi.org/10.1371/journal.pone.0289809 Text en © 2023 Habibu et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Habibu, Buhari
Aluwong, Tagang
Yaqub, Lukuman Surakat
Buhari, Hajarah Uwale
Makun, Hussaina Joan
Kawu, Mohammed Umaru
Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
title Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
title_full Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
title_fullStr Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
title_full_unstemmed Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
title_short Metabolic adjustments in neonatal dwarf and normal-sized goat kids: Relationship between serum metabolites and body size
title_sort metabolic adjustments in neonatal dwarf and normal-sized goat kids: relationship between serum metabolites and body size
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653417/
https://www.ncbi.nlm.nih.gov/pubmed/37972032
http://dx.doi.org/10.1371/journal.pone.0289809
work_keys_str_mv AT habibubuhari metabolicadjustmentsinneonataldwarfandnormalsizedgoatkidsrelationshipbetweenserummetabolitesandbodysize
AT aluwongtagang metabolicadjustmentsinneonataldwarfandnormalsizedgoatkidsrelationshipbetweenserummetabolitesandbodysize
AT yaqublukumansurakat metabolicadjustmentsinneonataldwarfandnormalsizedgoatkidsrelationshipbetweenserummetabolitesandbodysize
AT buharihajarahuwale metabolicadjustmentsinneonataldwarfandnormalsizedgoatkidsrelationshipbetweenserummetabolitesandbodysize
AT makunhussainajoan metabolicadjustmentsinneonataldwarfandnormalsizedgoatkidsrelationshipbetweenserummetabolitesandbodysize
AT kawumohammedumaru metabolicadjustmentsinneonataldwarfandnormalsizedgoatkidsrelationshipbetweenserummetabolitesandbodysize