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OptEnvelope: A target point guided method for growth-coupled production using knockouts
Finding the best knockout strategy for coupling biomass growth and production of a target metabolite using a mathematic model of metabolism is a challenge in biotechnology. In this research, a three-step method named OptEnvelope is presented based on finding minimal set of active reactions for a tar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653430/ https://www.ncbi.nlm.nih.gov/pubmed/37972019 http://dx.doi.org/10.1371/journal.pone.0294313 |