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Female sex protects against renal edema, but not lung edema, in mice with partial deletion of the endothelial barrier regulator Tie2 compared to male sex

BACKGROUND: The endothelial angiopoietin/Tie2 system is an important regulator of endothelial permeability and targeting Tie2 reduces hemorrhagic shock-induced organ edema in males. However, sexual dimorphism of the endothelium has not been taken into account. This study investigated whether there a...

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Detalles Bibliográficos
Autores principales:	van Leeuwen, Anoek L. I., Beijer, Elise, Ibelings, Roselique, Dekker, Nicole A. M., van der Steen, Marjolein R. A., Roelofs, Joris J. T. H., van Meurs, Matijs, Molema, Grietje, van den Brom, Charissa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653528/ https://www.ncbi.nlm.nih.gov/pubmed/37972011 http://dx.doi.org/10.1371/journal.pone.0293673

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