Determinants of DNMT2/TRDMT1 preference for substrates tRNA and DNA during the evolution

RNA methyltransferase DNMT2/TRDMT1 is the most conserved member of the DNMT family from bacteria to plants and mammals. In previous studies, we found some determinants for tRNA recognition of DNMT2/TRDMT1, but the preference mechanism of this enzyme for substrates tRNA and DNA remains to be explored...

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Detalles Bibliográficos
Autores principales: Li, Huari, Zhu, Daiyun, Yang, Yapeng, Ma, Yunfei, Chen, Yong, Xue, Pingfang, Chen, Juan, Qin, Mian, Xu, Dandan, Cai, Chao, Cheng, Hongjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653749/
https://www.ncbi.nlm.nih.gov/pubmed/37966982
http://dx.doi.org/10.1080/15476286.2023.2272473

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