Impact of PpSpi1, a glycosylphosphatidylinositol-anchored cell wall glycoprotein, on cell wall defects of N-glycosylation-engineered Pichia pastoris

In order to produce therapeutic glycoproteins modified with human-like N-glycan structures, much progress has been achieved toward the humanization of N-glycosylation pathways in yeasts. In this study, a Pichia pastoris mutant Glyco4, which has a humanized N-glycosylation pathway and could successfu...

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Detalles Bibliográficos
Autores principales: Zhu, Quanchao, Jia, Zuyuan, Song, Yuchao, Dou, Weiwang, Scharf, Daniel Henry, Wu, Xiaodan, Xu, Zhihao, Guan, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653784/
https://www.ncbi.nlm.nih.gov/pubmed/37606451
http://dx.doi.org/10.1128/mbio.00617-23

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