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Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector

Intramuscular vaccination of mice with the naked pBI-11 DNA plasmid targeting E6 and E7 of HPV16 and HPV18 via a conventional syringe and needle generates human papillomavirus (HPV) antigen-specific CD8+ T cell-mediated immune responses and therapeutic effects against the TC-1 tumor model. However,...

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Detalles Bibliográficos
Autores principales:	Peng, Shiwen, Tu, Hsin-Fang, Cheng, Michelle, Hu, Ming-Hung, Tsai, Hua-Ling, Tsai, Ya-Chea, Koenig, Chelsea, Brayton, Cory, Wang, Hao, Chang, Yung-Nien, Arend, Rebecca C., Levinson, Kimberly, Roden, Richard B. S., Wu, T. C., Hung, Chien-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653862/ https://www.ncbi.nlm.nih.gov/pubmed/37791765 http://dx.doi.org/10.1128/mbio.02121-23

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