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Host cell sensing and restoration of mitochondrial function and metabolism within Helicobacter pylori VacA intoxicated cells

Helicobacter pylori vacuolating cytotoxin A (VacA) is an intracellular-acting protein exotoxin that induces mitochondrial dysfunction and energy depletion within host cells. Although exposure to VacA results in mitochondrial dysfunction, one recent study revealed that, following limited exposure to...

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Detalles Bibliográficos
Autores principales: Seeger, Ami Y., Zaidi, Faisal, Alhayek, Sammy, Jones, Rachel M., Zohair, Huzaifa, Holland, Robin L., Kim, Ik-Jung, Blanke, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10653863/
https://www.ncbi.nlm.nih.gov/pubmed/37815365
http://dx.doi.org/10.1128/mbio.02117-23